Coombs Test Direct

2 Parameters

Also called: Direct Antiglobulin Test, DAT, Direct Coombs Test

Commonly prescribed for: Autoimmune hemolytic anemia, drug-induced hemolysis, hemolytic disease of the newborn (HDN), transfusion reactions

Home Collection

Report Delivery: Sample before 12 PM → by 8:30 PM today Sample after 12 PM → by 1 PM tomorrow

Call for Support

Age Group

All Ages

Sample Required

Blood

Test For

Men, Women

Contains

2 Tests

Tests available at

Home Collection

Preparations

No special preparation required

Expert Analysis

Case Studies

16 Jan, 2025

12 Minutes

Clinical Significance: The Direct Coombs Test (DAT) detects antibodies or complement proteins bound directly to the surface of circulating red blood cells, diagnosing autoimmune hemolytic anemia.

Why It's Done:

Detect antibodies bound to RBCs causing premature red cell destruction

Investigate autoimmune hemolytic anemia and immune-mediated blood disorders

Evaluate hemolytic disease of the newborn (erythroblastosis fetalis)

Assess delayed or acute transfusion-related hemolytic events

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