Fibrinogen Degradation Product (FDP) in Karimnagar

Know More About This Test

Fibrinogen Degradation Products (FDP) are fragments released into the bloodstream when the body breaks down blood clots. When a blood clot forms, plasmin dissolves the fibrin meshwork, resulting in degradation products (FDPs).

Measuring FDP levels provides crucial information about active clotting and fibrinolysis in the cardiovascular system.

It serves as an essential diagnostic marker for disseminated intravascular coagulation (DIC) and thromboembolic disorders.

Why Is This Test Recommended?

• Diagnosis of Disseminated Intravascular Coagulation (DIC)
• Evaluation of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE)
• Monitoring thrombolytic or anticoagulant therapy
• Investigating unexplained heavy bleeding or excessive clotting
• Assessment of obstetric complications like placental abruption

Understanding FDP Levels

• Normal reference level: Less than 5 mcg/mL (or < 10 mcg/mL depending on method)
• Significantly elevated FDP indicates abnormal active clot breakdown
• Commonly elevated in acute thrombosis, sepsis, malignancy, and severe liver disease

Preparation and Procedure

• No fasting required
• Blood sample collected via standard venipuncture in a special citrate tube
• Inform your doctor about any blood-thinning medications (heparin, warfarin, aspirin)

FAQs

• What are Fibrinogen Degradation Products? They are protein fragments left behind when your body naturally breaks down a blood clot.
• How does FDP differ from D-Dimer? While D-Dimer specifically measures cross-linked fibrin breakdown, FDP measures all breakdown products from both fibrin and fibrinogen.
• Is fasting required for the FDP test? No fasting is needed. The test can be performed at any time of the day.
• What causes elevated FDP? Conditions causing widespread clotting, such as DVT, pulmonary embolism, DIC, recent surgery, or trauma.
• Is FDP tested alongside other coagulation tests? Yes, it is routinely evaluated alongside PT/INR, aPTT, D-Dimer, and Fibrinogen for a complete coagulation profile.